Biological aspects of reactive nitrogen species
نویسندگان
چکیده
منابع مشابه
Clinical aspects of reactive oxygen and nitrogen species.
Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioa...
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Reactive oxygen species (ROS) play key roles in many pathogenic processes, including carcinogenesis, inflammation, ischemia-reperfusion injury and signal transduction. Also, reactive nitrogen species (RNS) cause various biological events such as neurodegenerative disorders. Sensitive and specific detection methods for ROS and RNS in biological samples should be useful for elucidation of biologi...
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Reactive species or free radicals include reactive oxygen and nitrogen species that are called reactive oxygen nitrogen species. Reactive oxygen species are formed as a natural by-product of the normal metabolism of oxygen and have significant roles in cell signaling and homeostasis. The reactive oxygen species are generated as a byproduct of biochemical reactions, in mitochondria, peroxisomes,...
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Nitric oxide is a cellular messenger produced by different cell types in an organism, both in physiological and pathological conditions (Snyder 1993; Beckman and Koppenol 1996; Beckman and Koppenol 1996; Beckman 1996; Colasanti and Suzuki 2000; Pacher, Beckman, and Liaudet 2007). Nitric oxide was first described in biology as the endothelium-derived relaxation factor for its effects on vasodila...
متن کاملBiological Activities of Reactive Oxygen and Nitrogen Species: Oxidative Stress versus Signal Transduction
In the past, reactive oxygen and nitrogen species (RONS) were shown to cause oxidative damage to biomolecules, contributing to the development of a variety of diseases. However, recent evidence has suggested that intracellular RONS are an important component of intracellular signaling cascades. The aim of this review was to consolidate old and new ideas on the chemical, physiological and pathol...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 1999
ISSN: 0005-2728
DOI: 10.1016/s0005-2728(99)00028-6